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February, 2007 > February 27, 2007


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New Genes Associated with Late-Onset Alzheimer's
(Source: Business Wire) - Celera announced the publication of research data identifying several candidate genetic markers associated with late-onset Alzheimer's disease. Two of these genes are PCK1, a gene that regulates blood glucose levels, and GALP, a gene thatregulates food intake, suggesting a link between Alzheimer's and irregular glucose/insulin levels.


Assessing Statins for Alzheimer Disease: Conflicting Evidence
(Source: Psychiatric Times) - The second report from the Alzheimer's Disease Cholesterol-Lowering Treatment trial was recently published. The first report suggested that lowering cholesterol levels with atorvastatin (Lipitor) could reduce cognitive and behavioral deterioration in persons with mild to moderate AD. This second report examined whether the apparent benefit is influenced by severity of cognitive impairment, circulating cholesterol levels, or apolipoprotein E genotype.


What Price Is My Father's Dignity?
(Source: The Daily Mail) - The Alzheimer's Society (UK) continues their legal challenge to reverse the NICE decision which bans the prescription of Aricept in the early stages of AD. Today the Daily Mail launches an emergency appeal for funds to help the charity fight its court battle.


Eldercare Planning: Steps To Take Now Before A Health Crisis
(Source: WNBC) - Although much of life is unpredictable, most of us work hard to prepare for what might happen. We install smoke alarms, click seat belts and stock up on cough syrup - because you never know. The secret to successful caregiving comes down to organization and planning. To prevent some emergencies and reduce the shock of others, imagine what might happen-and be ready.


An Implant to Treat Alzheimer's Disease
(Source: PharmaLive) - Debiopharm has announced its first patient has enrolled in a Phase II study using DEBIO-9902 SR implants (formerly ZT-1), which release monthly doses of Alzheimer's medication. The study will measure the safety and efficacy of the implants, in comparison to taking the drug orally.


Primary Progressive Aphasia
Letter to the Editor
I have been reading The Alzheimer's Daily News for nearly five years now. My husband was originally diagnosed with Early Onset Alzheimer's at age 55. He was later diagnosed with primary progressive aphasia. (PPA). I haven't read any articles in your newsletter about PPA. There are great similarities between the two diseases. Very little is known about PPA, and like Alzheimer's there are no cures, and no drugs to slow down the disease.